The National Institutes of Health determined not to renew the federal advisory committee’s charter for ME/CFS, or the CFSAC, by letting it expire. This committee was formed 16 years ago to share critical disease information and advice with the Secretary of Health. As a result, many were concerned that the NIH would no longer formally [...]
Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity.
Authors: Singh S, Stafford P, Schlauch KA, Tillett RR, Gollery M, Johnston SA, Khaiboullina SF, De Meirleir KL, Rawat S, Mijatovic T, Subramanian K, Palotás A, Lombardi VC. Link: https://www.ncbi.nlm.nih.gov/pubmed/29886183 Publication: Mol Neurobiol. 2018 Jan;55(1):633-641. doi: 10.1007/s12035-016-0334-0. Epub 2016 Dec 15. Myalgic encephalomyelitis (ME) is a complex, heterogeneous illness of unknown etiology. The search for biomarkers [...]
Nutritional modulation of the intestinal microbiota; future opportunities for the prevention and treatment of neuroimmune and neuroinflammatory disease.
Authors: Lombardi VC, De Meirleir KL, Subramanian K, Nourani SM, Dagda RK, Delaney SL, Palotás A. Link: https://www.ncbi.nlm.nih.gov/pubmed/29886183 Publication: J Nutr Biochem. 2018 Apr 19;61:1-16. doi: 10.1016/j.jnutbio.2018.04.004. [Epub ahead of print] The gut-brain axis refers to the bidirectional communication between the enteric nervous system and the central nervous system. Mounting evidence supports the premise that the intestinal microbiota [...]
Single-nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases.
Authors: Schlauch KA, Kulick D, Subramanian K, De Meirleir KL, Palotás A, Lombardi VC. Link: https://www.ncbi.nlm.nih.gov/pubmed/30120429 Publication: Int J Obes (Lond). 2018 Aug 17. doi: 10.1038/s41366-018-0181-3. [Epub ahead of print] BACKGROUND/OBJECTIVES: Obesity is an important risk factor for the development of diseases such as diabetes mellitus, hypertension, and dyslipidemia; however, a small number of individuals with long-standing [...]
August 17, 2018 6:00 pm to 9:00 pm The Grove at South Creek On Friday, August 17, Nevada Center for Biomedical Research (NVCBR) will host Cheers, its annual fundraising event to benefit treatment discovery for myalgic encephalomyelitis (ME) (also called ME/CFS). The event will take place from 6:00 p.m. until 9:00 p.m. at The [...]
The National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), and Centers for Disease Control and Prevention (CDC) recently assembled an external working group of international experts and patient advocates to develop a set of ME/CFS Common Data Elements (CDEs) for use in clinical research. The ultimate goal is to standardize [...]
FREE SHOWING November 2, 2017 • 6:00 p.m. William N. Pennington Health Sciences Building University of Nevada, Reno NVCBR and Simaron Research are pleased to bring UNREST, the Sundance award-winning documentary about ME, to our community. We are hosting a screening of this noteworthy film at the William N. Pennington Health Sciences Building on the [...]
This past May, several Nevadans, including NVCBR board member Nancy Ghusn, Julia Abts and her daughter Kendal, and NVCBR President and CEO Annette Whittemore, traveled to Washington, DC, to join other advocates from around the country in support of increased federal research funding. The Solve CFS Initiative organized this country-wide effort and kept things running [...]
Last spring, the NVCBR team wrote an extensive U54 grant to advance the diagnosis and treatment of ME/CFS through a collaborative research center to study ME/CFS with an emphasis on biomarker discovery and dysregulation of the gastrointestinal mucosal immune system. Although NVCBR was not chosen as one of the three research center sites, we will [...]
Authors: Khaibullin, Ivanova, Martynova, Cherepnev, Khabirov, Granatov, Rizvanov, Khaiboullina. Link: https://www.ncbi.nlm.nih.gov/pubmed/28572801 Publication: Front Immunol. 2017 May 18;8:531. doi: 10.3389/fimmu.2017.00531. eCollection 2017. Multiple sclerosis (MS) is an autoimmune neurodegenerative disease characterized by chronic brain inflammation. Leukocyte infiltration of brain tissue causes inflammation, demyelination, and the subsequent formation of sclerotic plaques, which are a hallmark of MS. Activation [...]