Jen Brea gives an impassioned TED talk about the realities of dealing with the disease known as ME or myalgic encephalomyelitis. Please listen as she tells about her struggles from the effects of the disease and the difficulties she encountered trying to find a doctor who could diagnose and treat her debilitating illness. Sharing this [...]
The Skin–Brain Connection Hypothesis, Bringing Together CCL27-Mediated T-Cell Activation in the Skin and Neural Cell Damage in the Adult Brain
Authors: Nataliya L. Blatt, Timur I. Khaiboullin,Vincent C. Lombardi, Albert A. Rizvanov and Svetlana F. Khaiboullina1, Link: http://journal.frontiersin.org/article/10.3389/fimmu.2016.00683/full Publication: Front. Immunol., 16 January 2017 Recent discovery of an association of low serum melatonin levels with relapse in multiple sclerosis (MS) opens a new horizon in understanding the pathogenesis of this disease. Skin is the main organ [...]
Humoral Immunity Profiling of Subjects with MyalgicEncephalomyelitis Using a Random Peptide MicroarrayDifferentiates Cases from Controls with High Specificityand Sensitivity
Authors: Sahajpreet Singh, Phillip Stafford, Karen A. Schlauch, Richard R. Tillett, Martin Gollery, Stephen Albert Johnston, Svetlana F. Khaiboullina, Kenny L. De Meirleir, Shanti Rawat, Tatjana Mijatovic, Krishnamurthy Subramanian, András Palotás, Vincent C. Lombardi Link: http://bit.ly/2h55uXC Publication: Mol Neurobiol (DOI 10.1007/s12035-016-0334-0) Abstract Myalgic encephalomyelitis (ME) is a complex, heterogeneous illness of unknown etiology. The search for biomarkers that can delineate [...]
You may have participated in Black Friday and Cyber Monday, today is your chance to participate in #GivingTuesday. This global day of giving reminds us to share our gifts with others in need during the holiday season. Join the #GivingTuesday movement by giving to Nevada Center for Biomedical Research (NVCBR) in support of local discovery [...]
Join us on November 29th for #GivingTuesday, a global day dedicated to giving. Following the widely recognized shopping events Black Friday and Cyber Monday, this day of generosity reminds us to share our gifts with others in need during the holiday season. We encourage you to participate in the #GivingTuesday movement by giving to Nevada [...]
We’re proud to announce that Nevada Center for Biomedical Research will be well represented at the 12th International IACFS/ME Research and Clinical Conference: Emerging Science and Clinical Care in Ft. Lauderdale, FL, from October 27-30, 2016. Dr. Vincent Lombardi, NVCBR Research Director, Dr. Kenny De Meirleir, NVCBR Medical Director, and Annette Whittemore, NVCBR CEO, will [...]
Failure of gut-associated pDCs to express membrane bound APRIL and BAFF prevents their ability to promote low-affinity IgA expression in ME/CFS
Authors: Vincent C Lombardi, Svetlana F Khaiboullina, Kenny L De Meirleir, Tanja Mijatovic, Jan Hulstaer Link: http://www.jimmunol.org/content/196/1_Supplement/137.4 Publication: The Journal of Immunology (2016) Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous illness characterized by a number of comorbid conditions; gastrointestinal (GI) dysregulation make up one subgroup of this disease. IgA is the most abundant antibody isotype found in mucosal secretions including [...]
Dr. Lombardi presented at the 2016 American Association of Immunologists annual meeting in Seattle, Washington.LEARN MORE
Transcriptional Analysis of Blood Lymphocytes and Skin Fibroblasts, Keratinocytes, and Endothelial Cells as a Potential Biomarker for Alzheimer’s Disease.
Authors: Mukhamedyarov MA, Rizvanov AA, Yakupov EZ, Zefirov AL, Kiyasov AP, Reis HJ, Teixeira AL, Vieira LB, Lima LM, Salafutdinov II, Petukhova EO, Khaiboullina SF, Schlauch KA, Lombardi VC, Palotás A. Link: https://www.ncbi.nlm.nih.gov/pubmed/27589530 Publication: J Alzheimers Dis. 2016 Sep 2. [Epub ahead of print] Alzheimer's disease (AD) is a devastating and progressive form of dementia [...]
Hantavirus Infection Suppresses Thrombospondin-1 Expression in Cultured Endothelial Cells in a Strain-Specific Manner.
Authors: Khaiboullina SF, Morzunov SP, St Jeor SC, Rizvanov AA, Lombardi VC. Link: https://www.ncbi.nlm.nih.gov/pubmed/27486439 Publication: Front Microbiol. 2016 Jul 19;7:1077. doi: 10.3389/fmicb.2016.01077. eCollection 2016. Hantavirus infection is associated with two frequently fatal diseases in humans: Hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). The pathogenesis of hantavirus infection is complex and not fully [...]